Synthesis and antibacterial activity of 2-amino chromenes arising cyanoiminocoumarins and β-naphthol
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Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives
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A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
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A series of 2-amino-4-aryl-3-cyano-7- (dimethylamino)-4H-chromenes was synthesized by condensation of 3- (dimethylamino) phenol, an aromatic aldehyde and malonitrile in ethanol containing piperidine. The assignments of the structure of all synthesized compounds were based on spectral data (IR, Mass and(1)H NMR). The cytotoxic activities of the synthesized compounds against six human tumor cell ...
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ژورنال
عنوان ژورنال: Organic Communications
سال: 2017
ISSN: 1307-6175
DOI: 10.25135/acg.oc.6.16.11.442